PUCL Job#1375 Sr Res. Assoc. SFO (Posted 27 June 2022)


Senior Research Associate, Flow Cytometry


At Lyell, our vision is to develop curative cell-based immunotherapies for solid tumor cancers. We have innovative science originating from our founder’s world class labs and a unique and disruptive approach to research and development. Our company is first and foremost focused on understanding the science. We are a learning organization, dependent on deep collaborative relationships between all of our colleagues, partners and founders. Our culture is based on Science, Respect, Collaboration and Courage and it reflects who we are and the environment we are creating.


The Flow Cytometry Senior Research Associate will be responsible for the daily operation of the Flow Cytometry Core to support scientists on various adoptive cell therapy projects withing the company. The role will be expected to perform routine instrument maintenance, basic trainings to new users, and troubleshooting to assist other scientists to run their flow cytometry assays smoothly. The role will also be expected to the maintenance and operation of cell sorters independently. The role will work with the other Flow Cytometry Core personnel to support the continued development and optimization of flow cytometry assays for use within the company.


  • Independent operation and troubleshooting of cell sorters
  • Maintain a highly functioning flow cytometry lab (e.g., daily instrument maintenance, troubleshooting, training to new users)
  • Develop and optimize flow cytometry assays (e.g., antibody titration, intracellular staining)
  • Draft standard operating procedures and quality standards in flow cytometry
  • Maintain inventory of flow cytometry reagents and supplies
  • Document experimental results and protocols


  • BSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field or a minimum of 7 years’ relevant experience within the area of focus 
  • MSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years’ experience within the area of focus


  • Demonstrated technical knowledge and hands-on experience of flow cytometry instruments and method development
  • Hands-on experience in operating BD cell sorters and/or experience with Cytek and Bio-Rad cell cytometery
  • Familiarity with FlowJo and/or FCS Express
  • Experience with basic cell biology protocols (i.e., microscopy, immunofluorescent staining, mammalian cell culture). 
  • Experience recording data in electronic notebook 


  • Ability to think critically and demonstrate troubleshooting and problem-solving skills
  • Ability to work independently and collaboratively among different project teams
  • Must have excellent oral and written communication skills
  • Ability to work efficiently, prioritize workflow, meet deadlines and balance competing priorities
  • Learn new protocols quickly and execute them successfully
  • Basic skills using Microsoft Office (Word, Excel, PowerPoint) and data analysis software packages FlowJo, FCS Express, and Prism

At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees.
Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.


The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.  This position requires you to work onsite at the Company’s facilities and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law).  Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law.  The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine.  The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.”


We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply.

 Application link:


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