Job Description Summary

The Translational and Correlatives Studies Laboratory (TCSL) is accepting applications for Research Specialist C position from qualified individuals seeking to work in fast-paced learning environment as a team member of the Flow Cytometer Assay and Technique Development group. The Research Specialist C will develop polychromatic flow panels to address the needs of sample analysis to support CCI Phase I clinical trials and to characteristic cell functionality and phenotype in clinical samples before and after treatment with gene or/and cellular immunotherapeutics.

Job Description

Primary responsibilities include performance of polychromatic flow cytometry on a conventional flow cytometer (an 18-color, 20 parameter Fortessa) and a spectral flow cytometer (a 64 channel Aurora) and the analysis of these high dimensional data by using FlowJo flow analysis software, R packages for flow cytometric data analyses, or equivalent informatic tools. He/she will also perform the maintenance of flow cytometers in TCSL and order the reagents for this group. This position would receive training and be required to qualify in flow sorting procedures. Additional duties include preparation of flow cytometry SOPs and presentation at internal, institutional, and external meetings. The candidate should be willing to work flexible hours that could include evenings and weekends.

This position is contingent upon funding.

Qualifications:

·       Bachelor’s degree in Biology or related science and 3-5 years of experience or equivalent combination of education and experience required. Master’s degree or PhD encouraged as well.

·       At least 2 years of experience on >8 color polychromatic flow staining and analysis.

·       Experience in analysis of high dimensional data using R language or the equivalent tools.

·       Knowledge of biostatistics is preferred.

·       Must be detail-oriented, highly organized, and able to manage multiple tasks, and deliver quality data.

·       Excellent oral and written communication skills.

·       Excellent interpersonal skills with the ability to operate effectively in a dynamic work environment.

·       Understanding of the connections between clinical, process/product development, and biological outcomes is preferred.

Lifeng Tian

PROJECT MGR. FLOW CYTOMETRY ASSAY & TECHNOLOGY DEV

Translational and Correlative Studies Laboratory (TCSL)

University of Pennsylvania

Smilow Center for Translational Research; South Tower

3400 Civic Center Blvd.

Bldg. 421; Floor 9; Office 102

Philadelphia, PA 19104-5157

Office phone (215) 647-4234

JR00022045 Research Specialist C (Translational & Correlatives Studies Laboratory) (Open)