PUCL Job#1230 - Scientist โ€“ Antibody Discovery Redmond, WA (posted April 20, 2019)

Scientist – Antibody Discovery 

Located in Redmond WA, SystImmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic bi-specific, and tri-specific antibodies, as well as antibody-drug conjugates (ADC's). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor. We are a group of highly experienced immuno-oncology scientists utilizing several technology platforms to develop world class advanced antibody-based drug therapies. 


About the position

This role is with the antibody discovery group.  Systimmune has developed a unique, efficient and extremely powerful antibody discovery platform.  This position would involve learning how to operate this platform and requires an intelligent individual who is enthusiastic about generating antibodies for the treatment of disease.  An ideal candidate will have a strong background in immunology, assay development, therapeutic antibodies and ideally Oncology.Although this group is primarily focused on antibody discovery it will also carry out some early stage drug development.  


Essential Duties and Responsibilities

  • Produce reports on new discovery targets
  • Run antibody discovery projects
  • Sort/Culture antigen specific B cells
  • Develop and miniaturize in vitro functional assays using primary immune cells and tumor cells
  • Screen antibodies for binding, function and kinetics at multiple stages of their development
  • Develop multi-specific antibodies
  • Work as part of a highly collaborative, interdisciplinary team
  • Prepare written reports and oral presentations on research projects



Education and Experience

  • PhD; MS; BS in Immunology, Biology, Biochemistry or a related field with (PhD); 10+ years (MS); 12+ years (BS) of relevant academic and/or pharmaceutical or biotech experience
  • Enthusiastic about discovering antibodies for the treatment of disease
  • Strong experience in developing immune cell assays is required
  • Strong background in immunology is required
  • Experience in drug development (especially with therapeutic antibodies) and oncology experience is highly desirable
  • Experience with Flow cytometry and ELISA is required, experience with other immunological assays would be ideal 
  • Octet, high throughput screening, and robotics experience would be desirable
  • Demonstrated drive for rigorous scientific excellence
  • Excellent time management and organizational skills
  • Excellent written, oral and interpersonal communication skills; strong team player


Systimmune offers a flexible schedule, competitive salary, and generous benefits package, including a health/dental/vision care package, employer retirement match, and paid time off! 

To Apply: Interested applicants should send their CV and cover letter to


NIH Electronic Directory
NSF Award Search
PubMed Central
NIH Reporter