EMD Serono is the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, a global pharmaceutical and chemical group. We strive to create value and benefit patients by transforming medical science into breakthrough solutions in our core therapeutic areas of neurodegenerative diseases, fertility and metabolic endocrinology, as well as oncology and autoimmune/inflammatory diseases as emerging areas of expertise.
Job Title: Scientist, Cell Sciences
PURPOSE OF THE ROLE
The Cell Sciences group, as part of the Protein and Cell Sciences (PCS) department, develops stable clonal cell lines for the purpose of manufacturing candidate biologic therapeutics. The Cell Sciences scientist will contribute to the drug discovery efforts of EMD-Serono by using state of the art methods and technologies to deliver to the project teams cell lines suitable for manufacturing and to bring our proteins into the clinic. The successful candidate will have a solid understanding of mammalian cell line development in an industry setting, from both a technical and a business perspective, as well as a strong foundation in cell and molecular biology. Experience in improving host cell lines and vector design, for the purpose of improving cell line performance, automated systems and productivity, is a plus.
MAIN INTERFACES
INTERNALLY:
-The candidate will interact with other members of the Protein and Cell Sciences group and will interface with a number of other scientists within the group, within NBE Technologies, and with Global Manufacturing and Supply staff as well.
EXTERNALLY:
-The candidate will foster relationships outside of the company as part of the effort to remain abreast of technical developments. This will include, vendors, other industry professionals as well as academics where appropriate.
KEY TASKS & RESPONSIBILITIES
•Development of stable, clonal cell lines for the expression of therapeutic candidate proteins.
•Technology development and/or evaluation to improve productivity of cell lines/process or throughput of cell line development or predictive models
•Productive interactions with other members of PCS, NBE organization, and Research, which enable projects and technologies to move forward
EDUCATION/LANGUAGES
•MS with up to 3-5 years of experience or BS and 5-7 years of experience.
•Fluent in English
PROFESSIONAL SKILLS & EXPERIENCE
•It is essential that the candidate has knowledge and experience of general cell culture techniques, including transfection, selection, cloning, small scale production models and protein expression. Direct experience with mammalian cell lines such as CHO, HEK-293 and NS/0 is preferred.
•Familiarity with instruments commonly used in the cell line generation lab: Guava, Cedex, ViCell, Octet, Cellavista, FACS Aria. Use of automated systems, is a plus.
•A strong background in cell and molecular biology, with experience in host cell engineering, cell culture process development, vector development, and/or development of novel assays to aid in cell line generation, is highly desirable.
•Must be able to effectively communicate both verbally and in written form with peers and senior management
•Familiarity with analytical assays, as they relate to protein product quality, is a plus.
•Familiarity with cell culture performance at various scales, from multi-well plates to bioreactors, is a plus.
•Experience with developing cell lines for multiple projects, within a platform framework, is highly desirable.
Equal Employment Opportunity
The Company is an Equal Employment Opportunity employer.
No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, or any other classification protected by applicable federal, state, or local law.
This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment.
Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to his/her Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because he/she made a good faith report of discrimination.
Interested candidates may apply via HERE
