Dr. Michael Andreeff, Section of Molecular Hematology & Therapy, Department of Leukemia at the University of Texas MD Anderson Cancer Center is seeking a talented and motivated individual who is interested in performing high-parametric, complex flow analysis. The successful candidate will help execute and analyze experiments using flow cytometry and mass cytometry (CyTOF) for high-speed acquisition of multi-parametric data in leukemias. Candidates should have experience working with human specimens, including sample preparation, and analysis of flow cytometry data. We are looking for a highly motivated individual with technical expertise in molecular and cell biology to conduct highly ambitious projects aimed at targeting drug-resistant leukemia stem cells.
The applicant will collaborate with established and committed investigators in this interdisciplinary research program which will involve cell sorting, cell culture (cell line and primary cells), CyTOF measurements, and signal processing.
Primary Responsibilities
Provide technical expertise for the optimization, execution, and analysis of flow cytometry experiments
Operate multi-laser, high-speed cell sorters and flow cytometers
Assist in the design of complex, multi-color flow cytometry experiments and optimize new antibody panels
Perform primary flow cytometry-based screening for the identification of novel therapeutics
After appropriate training, design and analyze and interpret high-parametric CyTOF experiments directed at studying leukemia-initiating cells. Experiments will be complemented by DNA and RNA sequencing to identify new signaling pathways and targets.
Requirements
B.S. degree or higher in Biological Sciences or other related field and 2+ years of multicolor flow cytometry experimental design, staining, data acquisition, and analysis experience
Attention to detail, excellent record keeping abilities, and willingness to work in a collaborative environment
Qualified applicants should have familiarity with hematopoietic cell populations
Familiarity with FlowJo is preferred; experience operating a FACSAria/Astrios is preferred
Interested candidates should email their CV to Dr. Andreeff at: MHTcytometry@gmail.com
