PREFACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  .ix

LIST OF ABBREVIATIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .   xiii

EXECUTIVE SUMMARY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  1

WORKSHOP FINDINGS, RECOMMENDATIONS, AND AGENCY RESPONSES . . .  3

FINDINGS FROM ATSDR HEALTH STUDIES

  1. ‘CLL-like’ B-cell Phenotypes Detected in Superfund Studies:
      Epidemiologic Methods and Findings
      SM SARASUA, RF VOGT, DC MIDDLETON, BA SLADE,
      MA MCGEEHIN, JA LYBARGER . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  Go To Article

  2. Laboratory Results in Eleven Individuals with B-CLL Like Phenotypes
      Detected in Environmental Health Studies
      RF VOGT, NK MEREDITH, J POWELL, SF ETHRIDGE,
      W WHITFIELD, LO HENDERSON, AND WH HANNON . . . . . . . . . .. Go To Article 

  3. B-cell Monoclonal Lymphocytosis in Three Individuals Living Near
      a Hazardous Waste Site
      GE MARTI, J MULLER, M STETLER-STEVENSON, AND
      N CAPORASO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  . . . Go To Article

IMMUNOBIOLOGY AND MOLECULAR GENETICS OF B-CELL
LYMPHOPROLIFERATIVE DISORDERS

  4. B-cell Differentiation and Risks for Neoplastic Transformation
      SR BAUER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  .   Go To Article

  5. Detection of Low Levels of B-cell Lymphoproliferative Disorders
      RL MAIESE AND RC BRAYLAN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .   Go To Article

  6. Early B-CLL Clones: Targeting the cCLLa for Diagnosis
      GB FAGUET. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .   Go To Article

  7. Flow Cytometric Detection of B-cell Non-Hodgkin's Lymphoma
      M STETLER-STEVENSON. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

  8. Infection-Dependent Low-Grade Lymphoid Neoplasia: How General is
      the MALT Lymphoma Paradigm?
      HM SHAPIRO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  Go To Article

  9  A Novel Technique to Analyze the Relative Concentration of the Expressed
      Immunoglobulin (Ig) V H Genes
      L RASSENTI AND TJ KIPPS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

10. Population Screening for B-cell Monoclonal Lymphocytosis using PCR
      and Flow Cytometry to Determine Immunophenotypes
      A JACK, S RICHARDS, P EVANS AND C WILKS . . . . . . . . . . . . . . . .  Go To Article

11. Analysis of Immunoglobulin Variable Heavy and Light Gene Expression
      in Chilean B-cell Chronic Lymphocytic Leukemia Patients
      PA BERTIN, E SANTIBANEZ, C RISUENO, C MELLER,
      F BARRIGA, G GREBE, AND P LIRA. . . . . . . . . . . . . . . . . . . . . . . . . . .   Go To Article

12. The Common Chronic Lymphocytic Leukemia Antigen (cCLLa)
      GB FAGUET. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

13. Receptors for Cytokine and Growth Factors on B-CLL Lymphocytes
      DP COLLINS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

14. The Role of T-cells in Chronic B-Lymphocytic Leukemia
      AD DONNENBERG AND VS DONNENBERG . . . . . . . . . . . . . . . . . . .   Go To Article

15. Cytokine Immunoregulation in B-CLL
      H FERNANDES AND E RAVECHE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article
 

RISK FACTORS AND EPIDEMIOLOGIC CONSIDERATIONS FOR
B-CELL LYMPHOPROLIFERATIVE DISORDERS

16. Occupational and Environmental Risk Factors for Chronic Lymphocytic
       Leukemia and Non-Hodgkin’s Lymphoma
      A BLAIR, SH ZAHM, KP CANTOR, AND MH WARD . . . . . . . . . . . . .  Go To Article

17. The Possible Association between Chronic Lymphocytic Leukemia
      and Exposure to Electric and Magnetic Fields
      D WARTENBERG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

18. Descriptive Epidemiology of Chronic Lymphocytic Leukemia (CLL)
      GE MARTI, FD GROVES AND MS LINET. . . . . . . . . . . . . . . . . . . . . . .  Go To Article

19. Familial B-CLL: Review of Literature and the NCI Familial B-CLL Registry
      N CAPORASO, L FONTAINE, J WHITEHOUSE AND
      GE MARTI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

20. B-CLL Is A Condition of Aging: An Editorial Comment
     WH ADLER. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

21. Autoimmune Disorders and Chronic Lymphocytic Leukemia (CLL)
      FD GROVES AND RF VOGT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go To Article

22. Proximity to Hazardous Waste Sites and B-Cell Lymphoproliferative
      Diseases: A Protocol for Population-Based Case-Control Analysis of
      Existing Data
      DC MIDDLETON, MH WARD, BA SLADE, CV LEE AND
      MD LEWIN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  . Go To Article

23. Characterizing B-Cell Lymphocytosis Identified in ATSDR Studies:
      Synopsis of a Protocol
      BA SLADE, DC MIDDLETON, MS MILLER AND
      RF VOGT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  . . . . . . . . . . . . . . . .  Go To Article

24. B-CLL Specific Questionnaire Emphasizing Risk Factors Associated
      with Environmental Exposures and Family History
      J LYBARGER. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  Go To Article

25. Informed Consent for Stored Tissue Samples: the NHANES III
      Experience
      KK STEINBERG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. Go To Article
 

SUMMARY

26. Summary of Epidemiology and Immunobiology
      RA CARTWRIGHT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  Go To Article
 

AUTHOR AND PARTICIPANTS INDEX . . . . . . . . . . . . . . . . . . . . .  Go To Article