Trop-2-dependent Recruitment of PKCα to the Cell Membrane

Movie 1 – MTE 4-14 cells transfected with Trop-2-mRFP1 and with PKCα–EGFP. Cytoplasmic vescicles containing Trop-2-mRFP1 are useful landmarks for the localization of PKCα–EGFP (empty cytoplasmic regions). Trop-2-mRFP1 and PKCα–EGFP dynamically colocalize in membrane ruffles and podosomes.

• pkca.mov
• pkca.mpg
• pkca.divx

Movie 2 – MTE 4-14 cells transfected with Trop-2-mRFP1 and with PKCδ–EGFP. Cytoplasmic vescicles containing Trop-2-mRFP1 are useful landmarks for the localization of PKCδ–EGFP (empty cytoplasmic regions). No significant colocalization of Trop-2-mRFP1 and of PKCδ–EGFP was observed.

• pkcd.mov
• pkcd.mpg
• pkcd.divx