Dear Clinical Flowers: We have a case of a male patient 50 years old with pancytopenia, splenomegaly and augmentation of retroperitoneal ganglia. We received BM sample and made some markers (see annex)with a non commun location in the CD45+ gating estrategy of a group of cells CD10+, CD19+, CD20+, CD22+ and HLA-DR+. These cells were large cells (FSC) and initially pathologist believed in myeloid derived cells but you will see markers. What other markers will be useful? Could be a lymphoma (origen)? JOHN MARIO GONZALEZ M.D., Ph.D. Facultad de Ciencias Pontificia Universidad Javeriana Fax 00 57 1 2850503 Phone 00 57 1 3208320 Ext 4085
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