Re: gfp spectral shifts?

From: Marty Bigos (mbigos@gladstone.ucsf.edu)
Date: Tue Aug 13 2002 - 09:49:14 EST


>Perhaps another (highly intersting) shift-inducing parameter exists
>: protein maturation. It is known that newly produced dsRed, a
>distant GFP homolog protein has a "greener" emission spectrum than
>the mature dsRed-protein. This might be the case for GFP as well ...
>
>Jan

Interesting! Do you have a reference on this? We have used dsRed here
only a little so haven't seen this behavior.

Thanks.

Marty

>
>Marty Bigos wrote:
>
>>
>>Hi -
>>
>>Does anyone know of shifts in the emission spectra of the various gfp
>>constructs due to intracellular pH, linkage to other proteins, etc.?
>>Thanks.
>>
>>
>>Marty
>>--
>>Marty Bigos
>>Director, Flow Core
>>Gladstone Institute of Virology and Immunology
>>Building 3 SFGH Rm 509
>>415-695-3832
>>
>
>--
>Jan Bayer, Ph.D.
>Fondation Jean Dausset - CEPH           Email : bayer@cephb.fr
>27, Rue Juliette Dodu			Tel : +33 1 53 72 51 14
>75010 Paris, France			    Fax : +33 1 53 72 51 28



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