Sorting Issues

From: Lee, Siow Fong (sflee@cha.ab.ca)
Date: Mon Aug 12 2002 - 13:22:59 EST


Hi All,

	I am posting the following questions for a colleague
(cmattar@ualberta.ca) who uses a Beckman Coulter Ultra for sorting:

	When sorting an event from a post-nuclear cell supernatant, during
the actual sort when the event is diverted into the sorting vessel, does
some of the cell lysate that the event was suspended in originally also
enter the sorting tube?  Will soluble proteins floating around in the
post-nuclear supernatant get sorted along with the event of interest?  I
realize the sample is taken up along with sheath fluid.  Does this also
dilute the non-specific soluble proteins which may contaminate a sorted
sample?  Thanks.

Siow Fong Lee
Department of Laboratory Medicine & Pathology
University of Alberta Hospital
Capital Health Authority
Edmonton, Alberta
Phone: (780)407-8067
Fax:  (780)407-8599
E-mail:  sflee@cha.ab.ca



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