different count in immunocytochemistry and FACS

From: gfjfgfg jgkljkl (rosettalazzaroni@yahoo.it)
Date: Sun Feb 03 2002 - 04:36:38 EST


I do immunocytochemistry for a cytoplasmic antigen and
the count at the microscope was very low (0.03%).
When I do the same reaction evaluated whith
FACScalibur the result  was 0%. However when the
immunocytochemistry was 0.3%, the FACS evaluated 2%.
This evaluation could be correct? May depend from
instrumental chracteristic rhater than error in
protocol because the percentage was low?
In general the count whith FACS is accurate and I can
appreciate 0.02 or 0.2% of cell staining?
Thank you for your replay



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