IL-2R CD25 vs. CD122

From: Maciej Simm (simmmmer@yahoo.com)
Date: Wed May 31 2000 - 15:08:50 EST


Greetings everyone,

This is more genetics than flow, but here it goes:

from my understanding CD25 binds to IL-2R on T cells and CD122 binds
to IL-2R on NK cells.

Are the molecules distinct genetically?

Do both consist of the alpha, beta and gamma chains?

Does one antibody interfere with the other? I mean, if I were to do
staining with 25 and 122, is it better to do them in distinct tubes?

also if anyone has any references type "review"(read- il-2r for
dummies) would you please forward me them?

regards,

maciej\

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