> ---------- > From: Maciej Simm > Sent: Thursday, 1 June 2000 5:38 > To: Cytometry Mailing List > Subject: IL-2R CD25 vs. CD122 > > > Greetings everyone, > > This is more genetics than flow, but here it goes: > > from my understanding CD25 binds to IL-2R on T cells and CD122 binds > to IL-2R on NK cells. > > Are the molecules distinct genetically? > > Do both consist of the alpha, beta and gamma chains? > > Does one antibody interfere with the other? I mean, if I were to do > staining with 25 and 122, is it better to do them in distinct tubes? > > also if anyone has any references type "review"(read- il-2r for > dummies) would you please forward me them? > > regards, > > maciej\ > > __________________________________________________ > > Hello Maciej, > > The following reference may help: > > "Surface and intracellular IL-2R expression on various resting and > activated populations involved in cell-mediated immunity in human > peripheral blood" S Hodge et al, Scand J Immunol, 51, 67-72, 2000. > > Regards, > Greg Hodge > (hodgeg@mail.wch.sa.gov.au) >
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