RE: Fluorochromes choice

From: Mario Roederer (roederer@drmr.com)
Date: Thu Oct 31 2002 - 13:59:36 EST


Oh, you B-cell immunologists.  You assume that all colors are used
for immunophenotyping.

That's like our current philosophy, that B cells are good for only
one thing:  making reagents with which we can distinguish important T
cell subsets!

mr


>Hi Michal,
>
>You are just another in the line of researchers who has an instrument which
>has used a misleading terminology in its description.  It does have three
>lasers, and two are fairly useful although there is no compensation
>circuitry between the 488 and 633 lasers (problem for APC and PE-Cy5
>channels).  The third laser as mentioned above is a "UV", but the problem is
>that the "UV" laser is too far down in the "UV" spectrum to be beneficial
>for the "UV" excitable fluorochromes. So, unfortunately, this laser
>configuration is totally useless when trying to use the currently available
>fluorochromes to do 6-color staining.
>
>Randy T. Fischer
>NIH/NIAMS
>Building 10, Room 6D57
>9000 Rockville Pike
>Bethesda, MD 20892
>(301) 594-3537
>fischer1@mail.nih.gov



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