Re: Paraformaldehyde disposal question

From: R. Thomas Leonard (tleonard@wistar.upenn.edu)
Date: Tue Sep 03 2002 - 19:46:42 EST


Tricia,

My understanding of US EPA regulations (and obviously this only applies if
you are in the US) is that when the hazardous constituent (in this case
PFA) comprises less than 1% of the waste solution, the solution is not
considered hazardous. Concentrations equal to or greater than 1% are
treated as hazardous waste. Accordingly, it seems to me that the contents
of your waste container may be poured down the drain with respect to the
[PFA]. Still, keep in mind that there may be other instances where it would
be less than prudent to dispose of a low concentration of a waste without
treatment (e.g. carcinogens, etc.), but that's certainly not the case with
0.01% PFA.

Regards,
Tom


X-Originating-IP: [63.103.226.238]
From: "Patricia Echeagaray" <pechado@hotmail.com>
To: cyto-inbox
Subject: Paraformaldehyde disposal question
Date: Mon, 02 Sep 2002 11:40:13 -0400
X-OriginalArrivalTime: 02 Sep 2002 15:40:13.0429 (UTC)
FILETIME=[0735A250:01C25297]
X-PMFLAGS: 34079360 0 1 6396.cnm
X-RCPT-TO: <tleonard@wistar.upenn.edu>

All,

At my current company, one of the scientists here insists that the waste
from counting fixed cells on the coulter counter should be saved and
disposed of as chemical waste. The cells (T'cells/PBMCs) are fixed in a
final concentration of 1% PFA. 100 ul are added to a 10 ml volume of
ISOTON. Can any of you tell me why...assuming this is common practice? At
other places I've been in the past, I'm fairly sure we just bleached it and
tossed it down the sink. That is what is done with the other 100 ul of
fixed cells (where PFA is much more concentrated, of course) since we make
200 ul total volume (100 ul 2%PFA + 100 ul cells).

Thank in advance!

Tricia Echeagaray


----------
Join the world’s largest e-mail service with MSN Hotmail. Click Here
At 11:40 AM 9/2/02 -0400, Patricia Echeagaray wrote:
> All,      other 100 ul of fixed cells (where PFA is much more
>concentrated, of course) since we make 200 ul total volume (100 ul 2%PFA +
>100 ul cells).   Thank in advance!   Tricia Echeagaray
>Join the world’s largest e-mail service with MSN Hotmail. Click Here
>



This archive was generated by hypermail 2b29 : Sun Jan 05 2003 - 19:26:20 EST