RE: Frozen Antibodies

From: Gerstein, Rachel (Rachel.Gerstein@umassmed.edu)
Date: Thu Aug 01 2002 - 16:44:49 EST


definitely worth testing, I had someone freeze PE conjugates once (gasp!!!)
and to my surprise they were fine.  Just be sure to spin out aggregates and
then check titer.

=======================================================
Rachel M. Gerstein, Ph.D.
Department of Molecular Genetics and Microbiology
Graduate Program in Immunology/Virology
University of Massachusetts Medical School
55 Lake Avenue North
Worcester, MA 01655-0002
(508) 856-1044
(508) 856-5920 (FAX)


> ----------
> From:		O'Donahue, Melanie .
> Sent:		Wednesday, July 31, 2002 11:22 AM
> To:	Cytometry Mailing List
> Subject:	Frozen Antibodies
>
>
> Fellow Flow-ers,
>
> Our flow fridge recently went haywire and froze our reagents. We are
> performing QC on
> all of them. So far, they look okay. Does anyone have any experience with
> the short
> and long term effects of freezing antibodies?
>
> On another note, we had a previous operator that kept all of the dry
> chemicals for
> making up reagents such as ammonium chloride lyse, PBS, etc., in the
> dessicator. The
> bottles don't specify this type of storage. Anyone have any thoughts on
> why the
> chemicals should stay in the dessicator?
>
> Thanks,
>
> Melanie O'Donahue, MT, ASCP
> Flow Cytometry Lead
> Mayo Clinic Scottsdale
> Odonahue.Melanie@mayo.edu
>
>



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