Re: Chromosome Sorting

From: John J. Fawcett (fawcett@lanl.gov)
Date: Tue Apr 23 2002 - 09:51:00 EST


				4/23/2002
Ryan,

	I can think of two approaches to sorting human chromosome #9.

	1. Use a human rodent hybrid containing chromosome #9 (Human
Chromosome-Specific DNA Libraries: Construction and Availability, M.A. Van
Dilla, L.L. Deaven, ..., Bio/Technology Vol. 4 June 1986 pp537-552), or,

	2. Counterstain using DAPI (Counterstaining Human Chromosomes for
Flow Karyology, Julianne Meyne,..., Cytometry 5:580-583 (1984))

				Joe Fawcett

>Quick Question for those who have done some human chromosome sorting...
>
>Is it possible to separate human chromosome 9 from 10-12?  In looking at
>papers with the normal Chromomycin A3 versus Hoechst bivariate histogram,
>and it always shows a 9-12 cluster.  If anyone has discovered another
>way(other dyes, reagents, etc...) to separate these, i'd love to know.
>
>
>Thanks,
>Ryan



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