Re: harvesting cultured macrophages

From: Robin Barclay (robin.barclay@ed.ac.uk)
Date: Tue Feb 26 2002 - 08:56:25 EST


I have found that lignocain will make adherent macrophages fall off
plastic - I haven't used the technique for quite a while, but I recall there
are publications in the area, so a medline search might turn up details of
the technique.
Robin Barclay

----- Original Message -----
From: "Dee Harrison-Findik" <duygu.harrison-findik@imvs.sa.gov.au>
To: cyto-inbox
Sent: 22 February 2002 02:09
Subject: harvesting cultured macrophages


>
> Dear Flowers
> I am isolating macrophages from human blood by the simple adherence
> technique.
> I am having difficulties to harvest the adhered macrophages by
conventional
> trypsinisation. Majority are still stuck to the TC. flask. Cell scraping
> does not yield very happy cells, either.
> Is there any specific reagent or technique which will lift off all (or
> majority) of the adhered macrophages as viable as possible ?
> Any input is greatly appreciated.
> Cheers
> Dee
>
>
>



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