Hi everyone, We received a CSF specimen for flow. Cell count was 5/ul. The sample was from a lymphoma patient with HIV positive. The physician would like to know if CSF was involved. We acquired as much cells as possible but the number of CD45 positive cell was still very low (87 events). About half of them (36 events) were CD19+ B-cell. Of these, 29 events were positive for kappa. How significant are these numbers? Would you call this CSF involvement with kappa restriction? How would you have reported this? Your opinion will be very much appreciated. Thanks. cy
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