b220+IgM- in mouse spleen

From: Derek Schulze (flow@post.queensu.ca)
Date: Wed Mar 21 2001 - 16:10:35 EST


We are seeing an increase of a B220+ IgM- population in the spleen of our
knock out mice. Are there any appropriate markers for mice to determine if
these are mature or immature B cells?

Would any of the following be appropriate?
CD2 (LFA-2)
IgD
CD80 (B7-1)
CD86 (B7-2)
Derek Schulze

Cancer Research Labs
Queen's University
353 Botterell Hall
Kingston, ON, K7L 3N6
(613) 533-6635

http://meds.queensu.ca/medicine/crl/



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