Derek, In addition, you may want to include some NK cell markers as well, such as NK1.1 or DX5, to look for expansion of NK cells in your mice. Many, if not all, NK cells, at least in B6 mice, coexpress B220, albeit to lower levels than B cells. Petter At 16:10 2001-03-21 -0500, Derek Schulze wrote: > >We are seeing an increase of a B220+ IgM- population in the spleen of our >knock out mice. Are there any appropriate markers for mice to determine if >these are mature or immature B cells? > >Would any of the following be appropriate? >CD2 (LFA-2) >IgD >CD80 (B7-1) >CD86 (B7-2) >Derek Schulze > >Cancer Research Labs >Queen's University >353 Botterell Hall >Kingston, ON, K7L 3N6 >(613) 533-6635 > >http://meds.queensu.ca/medicine/crl/ > Petter Höglund Microbiology and Tumor Biology Center (MTC) Karolinska Institute Box 280 S-171 77 Stockholm Sweden Tel: +46 8 728 62 01 Fax: +46 8 30 42 76 Mobile: +46 70 559 62 01 E-mail: petter.hoglund@mtc.ki.se
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