Re: CD10 expression

From: Anja Porwit (Anja.Porwit@ks.se)
Date: Tue Jan 30 2001 - 05:23:43 EST


Hello,
During last two years we have been doing flow on fine needle aspirates from
lymph nodes. There may be a significant population of CD10 positive B cells
in cases of reactive follicular hyperplasia. However, these CD10+ B cells
are negative for bcl-2 - the intracellular staining works nicely with DAKO
Intrastain.
Kind regards
Anna


At 09:55 2001-01-29 -0600, you wrote:
>
>Greetings;
>
>I have to agree with Dirk.  I rarely see any substantial expression of CD10
>(>10% of B cells) except in cases of B cell lymphoma.
>
>Sincerely yours;
>
>Safwat Girgis MD
>Regina, Saskatchewan, Canada
>
>Pasqua Hospital Laboratory Medicine
>4101 Dewdney Avenue.,
>Regina SK
>S4T 1A5
>Tel: 306 766 2229
>Fax: 306 766 2752
>
Anna Porwit
Hematopathology Lab.
Department of Pathology, Radiumhemmet
Karolinska Hospital, 171 76 Stockholm, Sweden
Anja.Porwit@ks.se
tel.:+46-851774518
fax.:+46-851775843



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