RE: ficoll of small volumes

From: Fischer, Randy (RFischer@therimmune.com)
Date: Tue Mar 28 2000 - 08:19:01 EST


Shawn,

Why ficoll mouse blood, is there a problem with ACK lysing?  We have
used this extremely well for phenotyping 100-200 mice by peripheral
blood every week.

Randy Fischer
TherImmune Research Corporation
9700 Great Seneca Hwy
Rockville, MD 20850
(240) 453-6256
RFischer@therimmune.com

> ----------
> From:		shawn_jackson
> Sent:		Friday, March 24, 2000 3:38 PM
> To:	Cytometry Mailing List
> Subject:	ficoll of small volumes
>
>
> hello all-
>
> I am searching for the best way to ficoll small volumes of blood
> (i.e.,
> 100-200 of mouse blood) efficiently during sample prep for flow.
>
> presently I am diluting the blood and spinning in 15 ml polypropylene
> tubes,
> but the cell layer can be frighteningly thin.
>
> can anyone suggest smaller tubes which have worked? our smaller
> 12x75mm tubes
> are awfully cloudy and hard to see through.
>
> thanks
>
> shawn jackson
> Harvard Univ
> Boston, MA
>
>



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