We have a pediatric male patient that presented in July of 1999 with neutropenia and a flow phenotype of 12% small (by FSC) cells positive for CD10,CD19,CD22, HLA-DRand 50% CD20, K and L negative. He is back in the clinic now with the exact same clonal population, still 12% and still the same phenotype. I have two questions about this? 1. Everyone says that hematagones are CD22 negative. Is it possible that these are hematagones even though they are strongly CD22 positive? 2. Are there any additional flow markers that we could use to help define these cells and diagnose the patient? Any help very much appreciated. Thanks, Brian Newsom Director, Flow Cytometry Center for Cell and Gene Therapy Baylor College of Medicine
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