How sure are you about the kappa/lambda negativity? Which antibodies do you use. How about TdT staining? EP Newsom, Brian S. wrote: > We have a pediatric male patient that presented in July of 1999 with > neutropenia and a flow phenotype of 12% small (by FSC) cells positive for > CD10,CD19,CD22, HLA-DRand 50% CD20, K and L negative. He is back in the > clinic now with the exact same clonal population, still 12% and still the > same phenotype. I have two questions about this? > > 1. Everyone says that hematagones are CD22 negative. Is it possible that > these are hematagones even though they are strongly CD22 positive? > > 2. Are there any additional flow markers that we could use to help define > these cells and diagnose the patient? > > Any help very much appreciated. > > Thanks, > Brian Newsom > Director, Flow Cytometry > Center for Cell and Gene Therapy > Baylor College of Medicine > > ------------------------------------------------------------------------ > > Part 1.2 Type: application/ms-tnef > Encoding: base64
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