Re: sorter sheath fluid

From: David Chambers (davidc@ccmi.salk.edu)
Date: Wed Dec 01 1999 - 14:15:24 EST


Hi David,

We use commercial "sterile water for irrigation USP" (the current batch is
in 1 litre bottles from Baxter).  It's expensive but not too bad if you buy it
in bulk and negotiate a discount.  Also it's definitely pyrogen free - we tested
it in a previous lab - and, er, sterile.  We make up sheath for the sorter with
this and Biosure preservative-free 8x concentrate.

-- David
Salk Institute Flow Cytometry Lab.


-------------------
On Mon, 29 Nov 1999, you wrote:
> Good day all.  I would like suggestions for a source of sterile, endotoxin free
> water or PBS.  I have been making my own PBS, but my water source, a lab
> filtration system that I'm not in charge of, isn't that great.  I have gotten
> contamination with algae and bacteria.  I can filter and autoclave to sterilize
> and remove particles, but I still have the endotoxin problem.  Sorting of
> lymphocytes for functional assays demands endotoxin free buffer.  Anybody else
> have this problem?
> 
> David McFarland
> Howard Hughes Medical Institute
> Flow Cytometry Facility
> Vanderbilt University Medical Center



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