Re: CD4+ and CD8+ T-cells in B-CLL?

From: Anna Porwit-MacDonald (Anja.Porwit@mb.ks.se)
Date: Mon Aug 30 1999 - 02:51:24 EST


Hi,
These cells are not thymocytes (they are TdT negative!).
They can be seen in very small numbers both in PB and BM of  normal donors
and increase after viral infections.
Best wishes
Anna

At 00:21 1999-08-27 PDT, you wrote:
>
>Dear colleagues,
>In a B-CLL peripheral blood sample (92% of lymphocytes are CD19+/CD5+) we 
>could detect 7% CD3+ cells, and 2.3% of these T-cells are CD4/CD8 double 
>positive.
>I would like to ask whether it can be a real population and if anyone knows 
>about these common thymocytes appearing in peripheral blood of B-CLL 
>patients.
>Thank you for any information,
>
>Julia B. Szeberenyi M.D.
>Dept. of Genetics, Cell-and Immunobiology
>Flow Cytometry Laboratory
>Semmelweis University of Medicine
>Budapest, Hungary
>
>
>______________________________________________________
>Get Your Private, Free Email at http://www.hotmail.com
>
>
Anna Porwit-MacDonald
Heamatopathology Lab.
Department of Pathology
Karolinska Hospital, Stockholm
anpo@mb.ks.se
tel.:+46-851775863
fax.:+46-851775843



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