Re: intracellular staining of viable cells

From: Deborah Berglund (umbbd@gemini.oscs.montana.edu)
Date: Mon Aug 30 1999 - 13:00:58 EST


Hi again,

As I posted just last week, we did this successfully in the early 90's
using electroporation, getting sorted labelled live cells back; method
published in Cytometry and J Imm Meth. (1990 or 91).  Also in Howard's
second version.

Deb Berglund
Montana State University

On Thu, 26 Aug 1999, Shirin Munir wrote:

> 
> 
> I was wondering to find some cell permeabilizing protocol.  My aim is to 
> stain an intracellular protein by indirect fluorescence antibody staining 
> but at the same time I don't want to kill the cells during fixing process.
> Do you know of any cell permeabilizing method to stain intracellular 
> protein which will stain the cell but cell will stay viable.  
> 
> Thank you very much for your help
> 
> 
> Shirin Munir
> 
> Dept. of Veterinary PathoBiology
> University of Minnesota
> 1971 Commonwealth Ave, St. Paul MN 55108
> 
> tel:612-624-8709
> fax:612-625-5203
> 
> 
> 
> 
> 



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