Sorry flow folks but I need to bother you with another IL-2 based question. If one gives IL-2 to T-cells they should proliferate (?), perhaps activated cells will start first/go faster than others (?), but... what I would like to know is has anyone any experience of dumping IL-2 on cells and looking at the phenotype - do they up-regulate CD38, or more importantly CD69 in response to the cytokine alone? Appreciate any replies. Doug Doug King Immunology Department Division of Investigative Science Imperial College School of Medicine Chelsea & Westminster Hospital 369 Fulham Road London SW10 9NH Tel: +44 (0)181 746 5979 Fax: +44 (0)181 746 5997 d.king@ic.ac.uk
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