COULTER™ CD31-RD1
CD31 antigen is known as the Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1). The CD31 antigen moderates monocyte, platelet and endothelial cell adhesion. This glycoprotein is involved in the transendothelial migration of leukocytes in inflammation. COULTER CD31-RD1 is a ready to use, liquid antibody for fundamental research and is not for clinical diagnostic use.
Light Scatter Histogram (CD31-RD1)
The light scatter pattern of lysed whole blood cellular populations is readily discernable on a FS vs. LSS dot density histogram. A gating region is set around the lymphocyte population.
Example Research Areas:Studies of T Cell Subsets
Morimoto, C. & Schlossman, S.F. Clin Exp Rheumatol, 1993, 11:241.
Torimoto, Y. J Immunol, 1992, 148:388.
Ashman, L.K. & Aylett, G.W. Tissue Antigens, 1991, 38:208.Cell Adhesion Studies
Simmons, K.L. et al. J Exp Med, 1990, 171:2147.
DeLisser, H.M. et al. Immunology Today, 1994, 15(10):490.
Log Fluorescence Histogram (CD31-RD1)
Single parameter histogram of a lysed whole blood sample stained with CD31-RD1 and gated on the lymphocyte region. The analysis region is based on an isotypic control.
Molecular Orientation
CD31 antigen is a member of the Ig
superfamily. It is a single chain, membrane
glycoprotein with a molecular weight
of 140 kD.
Cell Type
CD31 antigen is expressed on a broad range of hematopoetic and nonhematopoetic cells. It is not expressed on erythrocytes.
COULTER (TM)
CD31-RD1Specificity
CD31 is expressed as an endothelial cell junction molecule. This antigen is found on the majority of monocytes, platelets, and granulocytes. CD31 is preferentially expressed on the CD45RA+ population of CD4+ cells. This vascular cell adhesion molecule is capable of multiple ligand interactions.
Product Description
COULTER CD31-RD1 is in liquid form and is directly conjugated.
Concentration: 1µg/10 µL
Vial Contents: 0.5 mL
Isotype: Igg1
Part Number: 6607006
Chromosome 17
The CD31 gene is located on human Chromosome 17.
For Research Use Only. Not for Use in Diagnostic Procedures.
© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks
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