HLA FCXM Query - to dilute or not dilute?

From: Vivian Wu (ffwu@shaw.ca)
Date: Thu Dec 05 2002 - 20:41:11 EST


Hi HLA Flow Cytometrists,

I had posted this query fairly close to the U.S. Thanksgiving Day. Since CAPS/ASHI
is an American external quality assurance program, I would like to post it again. The
query is a follows:
We have noticed in the CAPS/ASHI Flow Crossmatch surveys that 75% of the labs are
diluting their serum and 25% uses it as neat serum. We were wondering ...1) what
serum (or sera) is being used as negative control, 2) what diluent is being used,
and 3)whether the negative control serum was also diluted as well.

Thanks for your help.

Regards,

Vivian Wu
Immunology Laboratory
Vancouver General Hospital,
B.C. Canada



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