Static Charge on Sort Collection Tube

From: Larry Polsky (lpolsky@vaccinex.com)
Date: Mon Nov 25 2002 - 14:15:58 EST


To all Sorters,

As a newcomer to sorting, I would appreciate any thoughts or comments on the need for inserting a static drain wire into non-conducting sort-collection tubes.

There are references in the literature (see below*) that note the possibility of sorted droplets being repelled by static charge that can accumulate on non-conducting, plastic collection tubes. The suggestion made in these references is to insert a grounded drain wire into the collection tube to dissipate any charge. However, two experienced sorters who I have asked about this have not seen static accumulation to be a problem and do not use drain wires.  The suggestions have also been made to use glass tubes (not always possible) or to coat non-conducting collection tubes with serum to achieve the same result.

Thanks very much in advance for your input on this question.

Larry Polsky
Vaccinex, Inc.
Rochester, NY

*e.g., Shapiro,  Practical Flow Cytometery,  2nd Ed, p. 108, and Dean, Cytometry 6:62-64 (1985)



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