GFP compensation

From: Efron, Philip A (efronpa@surgery.ufl.edu)
Date: Thu Oct 31 2002 - 11:20:27 EST


Once again, my name is Philip Efron and I work with murine dendritic cells
at the Unviseristy of Florida.  My new question is the following:  I am
transfecting mice in vivo with adenovirus expressing gfp.  I can isolate the
dendritic cell populations using CD11c and MHC II and I use 7-aad as a death
marker.  I was taught to compensate the FACS with CD8+ stained splenocytes.
Obviously, this doesn't work well for GFP.  Does anyone have any ideas on
how I can compenstate the machine so that I can look at expression of this
marker by flow from mouse lymphoid tissue?



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