Granulocytes fr monocytes by Flow

From: wkim1@caregroup.harvard.edu
Date: Fri Oct 04 2002 - 11:39:20 EST


Dear Flowers,

We are looking for a (or the) marker for granulocytes in human or monkey
PBMC to distinguish monocytes from them.  Gating monocytes in our Ficolled
PBMC based upon FSC/SSC plot alone does not do the job (cannot exclude
contaminating granulocytes, I believe).  The purpose of our PBMC prep is not
to eliminate granulocytes, but to evaluate granulocytic contribution to
monocyte population (i.e. enumerating granulocytes vs. monocytes).  To serve
this purpose, we need to have a pan-marker for human and monkey granulocytes
if there is such an antibody.  I would very much appreciate for your help
and expertise.

Sincerely,

Woong-Ki Kim, Ph.D.
BIDMC
Div Viral Pathogenes



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