RE: fluorochromes in food

From: Alan Bishop (ihiabis@imvs.sa.gov.au)
Date: Thu May 09 2002 - 22:35:26 EST


Sorry to contradict but Rhodamine B is not a food dye, at least if it ever
was it certainly isn't any longer, neither the FDA or ANZFA list it as such
and our chemical database here lists it as toxic.

	HAZARDOUS ACCORDING TO WORKSAFE AUSTRALIA CRITERIA.
	CONSIDERED A DANGEROUS SUBSTANCE ACCORDING TO DIRECTIVE 67/548/EEC,
POINT 4;
	AND HAZARDOUS ACCORDING TO OSHA 29 CFR 1910.1200 (USA).

	CAS RN:  81-88-9,69381-99-3   NIOSH:  BP 3675000   HAZCHEM:  None
	UN NO:	None  DG Class:  NONE  Pack Group:  None
	Sch Pois:  None  EPG:  NONE  IERG:  NONE

  CHEMWATCH HAZARD RATINGS
	      Flammability: 1
	      Toxicity: 2
	      Body Contact: 3
	      Reactivity: 0
	      Chronic effect: 1


	Scale: Min / Nil = 0, Low = 1, Moderate = 2, High = 3 and Extreme =
4.










	R Codes:  R22 R41 R51
       R40(3) R46(2)
	S Codes:  S53 S40 S35 S13
  R Statements:
		   • Harmful if swallowed.
		   • Risk of serious damage to eyes.
		   • Toxic to aquatic organisms.
		   • Exposure may produce irreversible effects*.
		   • May produce genetic damage*.
		   * (limited evidence).
  S Statements:
		   •  Avoid exposure - obtain special instructions before
use.
		   •  To clean the floor and all objects contaminated by
this material, use water.
		   •  This material and its container must be disposed of in
a safe way.
		   •  Keep away from food, drink and animal feeding stuffs.
  -----Original Message-----
  From: Michael Kuhn [mailto:mkuhn@helixresearch.com]
  Sent: Friday, 10 May 2002 00:30
  To: Cytometry Mailing List
  Subject: Re: fluorochromes in food


  Rhodamine B is used as a dye in foods and is fluorescent.  Of the food
dyes, Rhodamine B likely has the highest quantum yield in water and is
relatively insensitive to pH changes near neutral (pH 4 to 10).

  Michael Kuhn, President
  Helix Research
  Fluorescence Chemistry



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