Dead cell detection and intracellular cytokine staining

From: Adrian Smith (A.Smith@centenary.usyd.edu.AU)
Date: Sun Apr 14 2002 - 22:14:00 EST


Hi all,
  A while ago (it might even have been as long ago as 1998) this list
discussed the use of Ethidium Monoazide for the detection of dead
cells when doing intracellular staining (I think Mario was the first
to suggest it?). We are about to order some and get the technique
going in the lab here.

However, as we were discussing it someone in another lab mentioned
that he had been using apoptotic markers (in particular antibodies
against the active form of caspase-3) for the detection of apoptotic
and dead cells while doing intracellular staining.

Has anyone else tried this? Any comments?

Adrian Smith

--
______________________________________________
Adrian Smith (Research Officer)        T CELL BIOLOGY GROUP
Centenary Institute of Cancer Medicine & Cell Biology
Locked Bag No.6 Newtown, NSW 2042 AUSTRALIA.
Ph: (02) 9565-6198 Fax: (02)-9565-6103



This archive was generated by hypermail 2b29 : Sun Jan 05 2003 - 19:26:06 EST