Re: Flowcell in a FACStar Plus?

From: Howard Shapiro (hms@shapirolab.com)
Date: Thu Apr 04 2002 - 20:27:43 EST


Simon Monard wrote-

>Has anyone tried putting a flowcell in a FACStar Plus? How hard would it
>be to convert it
>into a two laser analyser? Does anyone have a quartz flowcell that I could
>install? I'm
>reluctant to heave it into a dumpster just yet and need an analyser that
>can look at
>GFP and YFP plus other stuff.

Why do you need the quartz flow cell? You will still be stuck with the
relatively low N.A. of the FACStar Plus collecting lens, and you won't get
problems with scatter measurements from a stream in air if you have the
droplet drive turned off.  So, unless you really need a closed fluidic
system, you might as well use the FACStar as is - well, almost. What I
would do is put on a 125 um or larger nozzle; that will give you a bigger
stream in air, enabling you to dispense with the blocker bar for
fluorescence collection (you may have to kludge up a field stop or
two).  And the frequency of clogging should go down substantially with the
larger nozzle.

-Howard



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