Dear Flow users, In order to avoid misunderstandings, I wanted to clarify the specificity issue about CD146. CD146 is constitutively expressed at a high level on all types of human endothelial cells (F Dignat-Georges et al 1997, Leucocyte Typing VI, 755-759). However, the CD146 expression is not restricted to the endothelium since it had been reported on smooth muscle, activated T-cells, fat cells, melanoma and on several other cell types as well (M. Mutin et al 1997, Tissue Antigens, 50, 449-458). Maxime
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