RE: 7AAD PROTOCOLS

From: Jáksó Pál (Pal.Jakso@aok.pte.hu)
Date: Tue Nov 27 2001 - 02:21:20 EST


Dear Rachel,

7AAD is may be better in some application because of the lower
crosstalking to the FL2 channel. Accordingly you can use it together
with PE stains. PI is very hard to compensate from the FL2. But if you
use only FITC as second stain (and nothing else) you can use both 7AAD
and PI for dead cell labeling.

Pal Jakso

University of Pecs
Faculty of Medicine
Dept. of Pathology
7643, Hungary
12. Szigeti str.


While this subject has come up: it seems like both 7AAD and propidium
iodide
can be (and are) used for detecting dead or apoptotic cells - are they
interchangeable ? If people have distinct preferences, what is the
difference ?

thanks,
Rachel



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