FACS Calibur

From: Carol Mazurek (mazurek@mpi.com)
Date: Mon Nov 05 2001 - 13:26:21 EST


I realize that the FACS Calibur multiwell autosampler is fairly new, but
is anyone actively using one?  Could you please share your successes and
failures with it?   Does it do what you need?  What would you change
about it?  Would you recommend it to others?

Is there anyone with experience at sorting cells using the FACS
Calibur?   I realize it has limitations, and I'm not expecting FACS
Vantage-quality sorting.   I have a cell line that is expressing a
recombinant protein and I want to sort the highest protein expressors
(e.g., top 1% or 10%) in that population.  What is the likelihood that I
could get 1000 - 2000 targeted cells at >98% purity after sorting for an
hour or two?


Carol Mazurek
Millennium Pharmaceuticals, Inc.
mazurek@mpi.com



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