Querry regarding BrdU

From: Preeti Shah (preetishah37@hotmail.com)
Date: Fri Nov 02 2001 - 11:28:31 EST




I want to place one querry in front of the forum.I hope that the forum will help me out.
I want to know that if I'm getting cell cycle arrest at one dose of any chemotoxic agent & I want to see that at any other dose I'm getting increased apoptosis,Can I couple the two techniques of BrdU labelling & Propidium iodide staining to see this effect.Or more intricately,If I want to demarcate the apoptotic fraction  precursor population(as being S phase arrested or G2-M phase arrested) ,how can I do this.
Or how can I know that which of population is going towards apoptosis(G0-G1 arrested or G2-M arrested population).
If somebody can help telling this,please reply me as soon as possible.
Thanx in advance.
Preeti
PhD student
India 


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