Re: BD$WORD values: Our findings for the LSR

From: David Novo (dnovo@ucla.edu)
Date: Wed Oct 31 2001 - 18:17:01 EST


Hi All,

I don't think that FCS standard is a farce at all. The farce is that
manufacturers don't adhere to it.  Even if Bob's wildest dreams came true,
and ISAC started recommending DICOM, and then the manufacturers started
using only the bits of the standard that appealed to them, then the DICOM
"standard" would not be worth much. The FCS standard specifies fields for
all of the information that is put in the BDWORD fields and the fact that
BD does not use them is a disservice to the flow community at large,
considering that most software will not know how to deal with them. and in
theory can change them at will.

Maybe there are some limitations to the FCS Standard in terms of validation
and tracking changes to the data but I think it does its job pretty well.

Although maybe my bias is somewhat tainted by not wanting to write a new
FCS data parser for FCS Express :-)

-Dave

At 09:38 AM 10/31/01 +1000, you wrote:

Dear All,
(As an aside, it nicely demonstrated what a mess (is farce too harsh a
term?) the FCS "standard" has become, and backs
up Bob Leif's recent comments regarding the inadequacies of the Flow
Cytometry Standard.)


At 09:38 AM 10/31/01 +1000, Geoffrey Osborne wrote:

>Dear All,
>         Following the number of replies I had regarding the BD$WORD
> values in the
>text section of CellQuest ProŠ 4.0.1 generated FCS files, I thought our
>findings might be of interest. (As an aside, it nicely demonstrated what a
>mess (is farce too harsh a term?) the FCS "standard" has become, and backs
>up Bob Leif's recent comments regarding the inadequacies of the Flow
>Cytometry Standard.)
>         On our LSR system the following holds true.
>BD$WORD3        P2 voltage
>BD$WORD5        P3 voltage
>BD$WORD7        P4 voltage
>BD$WORD9        P5 voltage
>BD$WORD11       P6 voltage
>BD$WORD55       P7 voltage
>BD$WORD24       P8 voltage
>
>For compensation, the formula is: (field value/250) * 100,
>thus for example in BD$WORD12   (FL1 - %FL2) a change from (10% -> 20%)
>compensation results in a field value change of 25 -> 50
>(10% -> 30%) : 25
>-> 75
>(10% -> 40%) : 25 -> 100
>(10% -> 50%) : 25 -> 125
>(10% -> 59.6%) : 25
>-> 149
>
>BB$WORD12   (FL1 - FL2)
>BB$WORD13   (FL2 - FL1)
>
>BD$WORD16   (FL1 -
>FL3)
>BD$WORD17   (FL3 - FL1)
>
>BD$WORD18   (FL1 - FL6)
>BD$WORD19   (FL6 -
>FL1)
>
>BD$WORD20   (FL2 - FL6)
>BD$WORD21   (FL6 - FL2)
>
>BD$WORD22   (FL3 -
>FL6)
>BD$WORD23   (FL6 - FL3)
>
>BD$WORD28   (FL2 - FL3)
>BD$WORD29   (FL3 -
>FL2)
>
>BD$WORD44   (FL4 - FL5)
>BD$WORD45   (FL5 - FL4)
>
>Hope this helps,
>Geoff
>Geoffrey Osborne
>
>Specialist, Flow Cytometry,
>John Curtin School of Medical Research,
>The Australian National University,
>Canberra, 0200, ACT. AUSTRALIA
>email: geoff.osborne@anu.edu.au
>http://jcsmr.anu.edu.au/facslab/facshome.html
>
>(61 2) 6125 3694.



This archive was generated by hypermail 2b29 : Sun Jan 05 2003 - 19:01:37 EST