Re: Conversion from Log to channel values

From: Dr. Wolfgang Beisker (beisker@GSF.DE)
Date: Wed Jun 07 2000 - 03:59:03 EST


Olindo,

I think the difference between a lin and a log measured channel (I can
only speak for the facsstar+) is not only as easy. You have on the
system a adjustment of the gain of the log amplifiers, which does NOT
influence the lin channels I think. Therefore the relation between lin
and log is more complicated, it looks like you have to add a constant k
to the equation.

Log values = k*10^(channel value/*scale factor)

k has to be determined empirically and depends on the adjustment on the
boards.


With best regards from Munich


Wolfgang



Olindo Assis wrote:
>
> Dear Flowers,
>
> It was clear for me, after I read the answers to my question about mean
> fluorescence channel analysis that most people suggested to analyze the data
> using the original number "mean" from the Log scale (10^0 - 10^4).
>
> However, I had analyzed most of my data after conversion of original data to
> channel values. Then, I start to have a problem because I did not want to go
> back and reanalyze all data since we have over 2,000 files to be analyzed.
>
> Therefore I was looking for a formula (mathematical expression) to convert
> the data back to Log values. Actually I found it on the CellQuest BD manual
> on chapter 6 "histograms". They say that to convert channel values to Log
> and vice-versa we just need to apply the following expression:
>
> Log values = 10^(channel value/*scale factor)
>
> where scale factor is 256 for a 0-1024 scale and 64 for a 0-256 scale.
>
> However, when I applied this formula to a group of data, that I had both
> values (Log and channel values), I did not find this formula as the right
> one to convert the data one to another.
>
> Does anyone have any experience with this.
>
> Best regards,
> Olindo

--
Dr. Wolfgang Beisker
GSF - National Research Center of Environment and Health
Flow Cytometry Group
Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany



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