Trop-1 is expressed in fetal progenitor cells in human epidermis. This may also be true for liver and othe epithelia. Saverio Alberti Head, Lab. of Experimental Oncology Department of Cell Biology and Oncology Consorzio Mario Negri Sud 66030 Santa Maria Imbaro (Chieti), Italy Phone: (39-0872) 570.293 FAX: (39-0872) 570.412 E-mail: alberti@cmns.mnegri.it On Wed, 19 Apr 2000, Dana Levasseur wrote: > > Hello All, > > Maybe this is a question the flow community can tackle? We are looking for > an antibody specific for hepatocytes. Specifically, we are trying to > differentiate between cells of erythroid versus other origins in fetal liver > and were wondering if a "hepatocyte specific marker" existed. TER119 is the > logical option for the erythroid marker. Also, I know the question was > posed to the group a short time ago, but does there exist an erythroid > marker that can differentiate more primitive precursors such as BFU-E, > CFU-E, or normoblasts? Presumably, TER119 stains these cells, but it also > stains retics. and mature erythrocytes. > > Many thanks in advance, > > > Dana Levasseur > University of Alabama at Birmingham > Bevill Biomedical Research Building, Rm. 870 > 845 19th Street South > Birmingham, AL 35205 > > phone: (205)-934-1963 > e-mail: dnl@uab.edu >
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