mouse/human hepatocyte specific marker

From: Dana Levasseur (Dana_Levasseur@microbio.uab.edu)
Date: Wed Apr 19 2000 - 02:14:42 EST


Hello All,

Maybe this is a question the flow community can tackle?  We are looking for
an antibody specific for hepatocytes.  Specifically, we are trying to
differentiate between cells of erythroid versus other origins in fetal liver
and were wondering if a "hepatocyte specific marker" existed.  TER119 is the
logical option for the erythroid marker.  Also, I know the question was
posed to the group a short time ago, but does there exist an erythroid
marker that can differentiate more primitive precursors such as BFU-E,
CFU-E, or normoblasts? Presumably, TER119 stains these cells, but it also
stains retics. and mature erythrocytes.

Many thanks in advance,


Dana Levasseur
University of Alabama at Birmingham
Bevill Biomedical Research Building, Rm. 870
845 19th Street South
Birmingham, AL  35205

phone:  (205)-934-1963
e-mail:  dnl@uab.edu



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