Re: A letter from AIDS Center

From: Tom Mc Closkey (thomasm@nshs.edu)
Date: Wed Apr 19 2000 - 12:19:06 EST


HIV/AIDS Patients Support Foundation - Georgia wrote:
>
> What is and how much is the prognostic importance of CD38 T cells
> subsets as activation markers in HIV infection.
>

	CD8+CD38+ cells have been reported to add to the prognostic value of
CD4 cell counts in order to predict disease progression.  This finding
is shown in:

Giorgi et al, Elevated levels of CD38+CD8+ T cell in HIV infection add
to the prognostic value of low CD4+ T cell levels: results of 6 years of
followup, J Acq Imm Def Syn, 6: 904-912, 1993.

Liu et al, Elevated relative fluorescence intesity of CD38 antigen
expression on CD8 T cells is a	marker of poor prognosis in HIV
infection:  results of 6 years of followup, Cytometry, 26: 1-7, 1996.

Tom

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Thomas W. Mc Closkey, Ph. D., Director of Flow Cytometry
North Shore University Hospital, New York University School of Medicine
Boas Marks Biomedical Research Center, 350 Community Drive
Manhasset, Long Island, New York 11030
ph:  516-562-4844 [office], 516-562-1135/4641 [lab]  fax:  516-562-2866
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