Re: FACSComp QC

From: Sharon F Vogt (svogt@bellsouth.net)
Date: Thu Mar 30 2000 - 08:48:49 EST


>Do you run this each time you start up the cytometer or only
>occasionally.  I have been told that I should run FACSComp each day that
>I run samples, but the beads are fairly expensive.  Any alternatives?

Hi-

I've been doing this daily, but (this week, as a matter of fact) have come
to think that it may be unneccesary. Because the pmt voltages jump around a
bit more than the Scan's ever did, I thought I might run FACScomp once a
week, Mondays, and a CDCheck tube (say, 3/8/45/4). Then, on subsequent days,
run the CDCheck tube and compare the fluorescent intensities of a given
population to the Monday locations of same.

I can determine the allowable difference in fl intensity from day-to-day or
the week's beginning-end by reviewing a few weeks of data. Potential
problems are degradation of CDChex (over one week??) and documentation of
sensitivity measurements daily. Any thoughts on that?

sharon

Sharon F. Vogt
svogt@bellsouth.net
Dekalb Medical Center
Atlanta, GA



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