Dear Flow-ers, We got a bone marrow sample from a 5-year-old boy who has anaemia, thrombopenia and leukopenia, returning febrile status, leg pain. We found that only 10% of bone marrow cells expressed CD45. 90% of the blast-like cells were HLA-DR+ and CD10+, but they do not express CD19. The percentage of CD34+ cells are also very low (0.1%). We could not detect neither CD33 or CD13. 5% of the cells were positive for CD3, CD5 or C7. What kind of malignancy can this be? I would appreciate any comments. Julia Julia B. Szeberenyi M.D Dept. of Genetics, Cell-and Immunobiology Laboratory of Flow Cytometry Semmelweis University of Medicine H-1089 Budapest, Nagyvarad ter 4 Hungary email: szebjul@net.sote.hu fax:+36-1-303-69-68
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