NK Markers in Cynos

From: jill.omerza@pharma.novartis.com
Date: Thu Feb 07 2002 - 07:48:51 EST


Hi everyone,
I was hoping to find someone who has some experience using markers to
identify NK cells in Cynomologous Monkey peripheral blood.  I have used a
mixture of CD56+16 from Pharmingen (clones MY31 + 3G8) and after reading an
article that states that CD56 may be identifying monos and not NK cells in
Rhesus Monkeys, I have been doubting whether what I am measuring is just NK
cells.
Does anyone know if this is also true in Cynos as well?   Are there any
better markers available to measure NK cells, or is it sufficient to
measure those cells that are just CD16 positive in this species.
Any and all comments are appreciated.

Jill Omerza
Novartis Pharmaceutical Corp.
1 Health Plaza
East Hanover, New Jersey 07936
973 781-8700



This archive was generated by hypermail 2b29 : Wed Apr 03 2002 - 11:59:23 EST