Did you look at the expression of CD5 and CD10 in these cells? Maybe you are looking at mantle zone cells that can have weak SIg expresion? Kind regards Anna At 15:51 2000-12-08 -0500, you wrote: > Gating on these larger cells (by light scatter) shows they are >kappa and lambda negative. Initial gating is done on the CD45+ cells by SS >vs CD45-TC. normal, and other times atypical (but not enough to call it >malignant). Are these cells some sort of normal, B-cells with neither >kappa or lambda? Or do they represent a possible pre-malignant state? How >do you (if you have seen this scenario) report this out? Thanks in >advance Andrea Illingworth Dahl-Chase Diagnostic Services Flow Cytometry >Bangor, Maine Anna Porwit Hematopathology Lab. Department of Pathology, Radiumhemmet Karolinska Hospital, 171 76 Stockholm, Sweden Anja.Porwit@ks.se tel.:+46-851774518 fax.:+46-851775843
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